Selected Publications

Endothelial deletion of p53 generates transitional endothelial cells and improves lung development during neonatal hyperoxia

Vila Ellis L, Bywaters JD, Chen J. Endothelial deletion of p53 generates transitional endothelial cells and improves lung development during neonatal hyperoxia. bioRxiv 2024.05.07.593014; doi: https://doi.org/10.1101/2024.05.07.593014 (corresponding author)

Epithelial Vegfa specifies a distinct endothelial population in the mouse lung

Vila Ellis L, Cain MP, Hutchison V, Flodby P, Crandall ED, Borok Z, Zhou B, Ostrin EJ, Wythe JD, Chen J. Epithelial Vegfa specifies a distinct endothelial population in the mouse lung. Developmental Cell 52, 617-630; doi: https://doi.org/10.1016/j.devcel.2020.01.009

Neonatal hyperoxia induces activated pulmonary cellular states and sex-dependent transcriptomic changes in a model of experimental bronchopulmonary dysplasia

Xia S*, Vila Ellis L*, Winkley K, Menden H, Mabry SM, Venkatraman A, Louiselle D, Gibson M, Grundberg E, Chen J, Sampath V. Neonatal hyperoxia induces activated pulmonary cellular states and sex-dependent transcriptomic changes in a model of experimental bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2023 Feb 1;324(2):L123-L140. doi: 10.1152/ajplung.00252.2022. (*contributed equally to this work)

Endothelial cells in the lung

Vila Ellis L, Shuet Lin Kong C, Chen J. Endothelial cells in the lung. In: Nikolic MZ, Hogan BLM, eds. Lung Stem Cells in Development, Health and Disease (ERS Monograph). Sheffield, European Respiratory Society, 2021; pp. 144–157 [https://doi.org/10.1183/2312508X.10009820] (co-corresponding author)

A cell-centric view of lung alveologenesis

Vila Ellis L, Chen J. A cell-centric view of lung alveologenesis. Developmental Dynamics. 2020;1-15. https://doi.org/10.1002/dvdy.271